via The Cade Museum for Creativity and Invention | The Cade Museum Prize.

Over 120 inventors and entrepreneurs from the State entered to win the prestigious Cade Museum Prize. Today, only the “Final Four” remain, all vying for the $50,000 reward and the title of 3rd Annual Cade Museum Prize Winner, which will be revealed at a gala event on May 11 at the Santa Fe Fine Arts Hall in Gainesville.

The four teams – one from Orlando, one from Tampa, and two from Gainesville – reflect the strength of Florida’s innovators in the fields of health and life sciences:

eCath, developed by Phil Hipol and Stuart Hart at the University of South Florida in Tampa, is an electronic catheter stethoscope that enables doctors to listen to sounds within the body using non-invasive electronic sensors attached to a catheter. The eCath device can be used for highly sensitive fetal heart rate monitoring, more sensitive monitoring of heartbeat and respiration in certain patients, and also to improve outcomes in hysterectomies.

NanoDLSay, an invention that resulted from work by Qun Huo of Nano Discovery in Orlando, represents an entirely new approach to detecting, identifying and analyzing biomolecules. By measuring unique interactions between gold nanoparticles and biomolecules, this technology can provide information on disease markers – including cancer – that has never before been feasible, possibly leading to breakthroughs in understanding and diagnosing these diseases.

Chlorine Dioxide is the most effective, safe disinfectant known, but until now its very short shelf life has made it impractical for use commercially. RelīOx Corporation and Ian Knapp, of Gainesville, have developed a simple system that can create chlorine dioxide from water and especially created plastic beads that are individually housed in rechargeable cartridges. This method of disinfection can be an important new public health tool in hospitals, food processing, restaurants and public transportation.

Transdermal Insulin Patch, a technology under development to deliver large molecules – including insulin – through the skin and into systemic circulation, was developed by Stephen Hsu of Prometheon Pharmain Gainesville. This patch promises to eliminate the need for needles and injections for diabetics and others receiving these types of drugs.

The Final Four were chosen from 120 entries by almost 30 judges in 3 rounds.  The judging panels included entrepreneurs, venture capitalists, and technology transfer specialists.